Enzymit and Cosun attain a significant turning point in sustainable biomanufacturing, producing high-purity hyaluronic acid with an unique cell-free procedure that provides unequaled control over molecular profile.
REHOVOT, Israel and BREDA, Netherlands, Nov. 10, 2025/ PRNewswire/– Enzymit, an artificial biology business pioneering cell-free biomanufacturing, in collaboration with Cosun, a farming cooperative and leader in sustainable, circular production of plant-based active ingredients, revealed effective pilot-scale production at the 200-liter scale of hyaluronic acid (HA) utilizing an enzyme-only, cell-free procedure. The project produced multi-kilogram amounts of high-purity HA, showing remarkable procedure performance and item consistency compared to standard fermentation.
Hyaluronic acid is amongst the world’s most important biopolymers, with applications covering from dermal fillers and injury recovery to drug shipment and tissue engineering. The worldwide hyaluronic acid items market price at $ 9.43 B in 2025 is forecasted to grow to $ 15.94 B by 2035, highlighting the immediate requirement for high-purity, high-performance biomaterials.
Enzymit’s cell-free procedure is the very first to let producers set the size of hyaluronic acid throughout production. Utilizing the exact same enzymatic procedure, it can make HA in specified sizes from about 10 kDa to about 4 MDa with a really narrow size circulation, changed through basic production settings instead of altering enzymes or organisms.
” We are honored to have actually belonged of Enzymit’s journey in scaling their laboratory procedure to pilot scale, and extremely happy that procedure advancement and first-ever factory operation succeeded based upon our existing producing possessions. It’s amazing to see this cell-free innovation end up being a commercial truth within such a brief quantity of time,” stated Marie Dobenesque, Chief Innovation Officer, Cosun RD&I.
This is a presentation of Enzymit’s cell-free biomanufacturing platform using AI-designed enzymes, efficient in manufacturing complicated bioproducts without making use of living cells – much faster, cleaner, and more effectively than ever in the past.
” This isn’t simply an advancement in hyaluronic acid production – it’s a look into the future of how we make particles,” stated Gideon Lapidoth, CEO of Enzymit. “By integrating AI-designed enzymes with a robust cell-free system, we have actually gotten rid of biological traffic jams and shown that accuracy production of biomolecules is no longer restricted by what cells can or can’t do.”
About Enzymit
Established to transform green chemistry, Enzymit has actually established a cell-free biomanufacturing method, powered by AI-designed enzymes, weding the very best of biology and chemical engineering. By changing cell-based techniques with enzyme-driven synthesis, Enzymit can lastly make bio-production a really competitive production innovation. Backed by Khosla and Grove Ventures, Enzymit is developing a future where any particle can be produced as needed. To read more, go to https://www.enzymit.com/
About Cosun
Cosun is a global farming cooperative. We make every effort to open the complete capacity of plants and are devoted to making scrumptious, healthy and circular food and active ingredients every day. Cosun produces plant-based food and food active ingredients, animal feed and green energy. With over 125 years of experience, we work cooperatively with providers, 8,100 growers and more than 4,600 staff members in Europe, Asia and The United States And Canada Business Aviko, Cosun Beet Business, Duynie, Cosun Protein and Sensus become part of Cosun. Together, Cosun attained a yearly turnover of EUR 3.4 billion in 2024. More info: www.cosun.com
To learn more, please contact:
Gideon Lapidoth
CEO, Enzymit
gideon@enzymit.com
+972-506847081
Picture: https://mma.prnewswire.com/media/2818450/Enzymit_HA_Production.jpg
SOURCE Enzymit